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Formulation Development and Evaluation of Oro-Dispersible Paediatric Paracetamol Tablets

Maganga, M.B. (Muhimbili University of Health and Allied Sciences, 2016)

Background: Paracetamol is a drug which is administered, both parenterally and orally though mostly orally, for management of pain and fever. Paracetamol liquid dosage forms for paediatrics (syrups and elixirs) dominate ...
Formulation development of artemether 20 mg/ lumefantrine 120 mg fixed dose combination tablet

Kaswamila, D. (Muhimbili University of Health and Allied Sciences, 2020)

ABSTRACT Background: The World Health Organization (WHO) recommends artemisinin based combination therapies (ACTs) for the treatment of uncomplicated malaria caused by P. falciparum parasite. By combining two active ...
Framing the Drivers of Antimicrobial Resistance in Tanzania

47. Durrance-Bagale, A.; Jung, A.; Frumence, G. (Muhimbili University of Health and Allied Sciences, 2021)

ABSTRACT Despite global awareness of the key factors surrounding antimicrobial resistance (AMR), designing and implementing policies to address the critical issues around the drivers of AMR remains complex to put into ...
FRelation between early introduction ofsolid food to infants and their weight and illnesses during the first two years oflife

Forsyth, J.S.; Egston, S.A.; CIark, A.; Florey, CV.; Howie, P.W. (BMJ, 1993)

Objective-To assess the relations between early introduction of solid food and infant weight, gastrointestinal illness, and allergic irnesses during the first two years oflife. Design-Prospective observational study ...
Frequency of MED12 mutation in relation to tumor and patient's clinical characteristics: A meta-analysis

Li, H.; He, C.; Nelson, W. (2021)

ABSTRACT Mediator complex subunit 12 (MED12) is the most frequently mutated gene in uterine leiomyomas (ULs)-with a frequency of up to 85%-suggesting that it plays key roles in the pathogenesis of ULs. However, there is ...
From a Lancet Commission to the NCDI Poverty Network: reaching the poorest billion through integration science.

Bukhman, G.; Mocumbi, A.O; Gupta, N. (Muhimbili University of Health and Allied Sciences, 2021)

ABSTRACT Since its inception in 2016, the Lancet Commission on reframing non-communicable diseases (NCDs) and injuries (NCDIs) for the poorest billion (Lancet NCDI Poverty Commission) has been steadily building a foundation ...
From coitus to concurrency: sexual partnership characteristics and risk behaviors of 15–19 year old men recruited from urban venues in Tanzania

Yamanis, T.J; Doherty, I.A; Weir, S.S; Bowling, J.M; Kajula, L.J; Mbwambo, J.K; Maman, S. (Springer, 2012)

Understanding the uptake and patterns of sexual partnerships of adolescent males reveals their risky behaviors that could persist into adulthood. Using venuebased sampling, we surveyed 671 male youth ages 15–19 from ...
From papers to practices: district level priority setting processes and criteria for family planning, maternal, newborn and child health interventions in Tanzania

Chitama, D.; Baltussen, R.; Ketting, E.; Kamazima, S.; Nswilla, A.; Mujinja, P.G.M. (BioMed Central, 2011)

Background: Successful priority setting is increasingly known to be an important aspect in achieving better family planning, maternal, newborn and child health (FMNCH) outcomes in developing countries. However, far too ...
Fructose-1, 6-diphosphate (FDP) as a novel antidote for yellow oleander-induced cardiac toxicity: a randomized controlled double blind study.

Gawarammana, I.; Mohamed, F.; Bowe, S.J.; Rathnathilake, A.; Narangoda, S.K.; Azher, S.; Dawson, A.H.; Buckley, N.A. (BioMed Central, 2010)

BACKGROUND: Cardiac toxicity due to ingestion of oleander plant seeds in Sri Lanka and some other South Asian countries is very common. At present symptomatic oleander seed poisoning carries a mortality of 10% in Sri ...
Fungal surface and innate immune recognition of filamentous fungi.

Figueiredo, R.T.; Carneiro, L.A.; Bozza, M.T. (2011)

The innate immune system performs specific detection of molecules from infectious agents through pattern recognition receptors. This recognition triggers inflammatory responses and activation of microbicidal mechanisms by ...
G-CHF Investigators. Health-Related Quality of Life and Mortality in Heart Failure: The Global Congestive Heart Failure Study of 23,000 Patients from 40 Countries

Johansson, I.; Joseph, P.; Balasubramanian, K. (Muhimbili University of Health and Allied Sciences, 2021)

Background: Poor health-related quality of life (HRQL) is common in heart failure (HF), but there are few data on HRQL in HF and the association between HRQL and mortality outside Western countries. Methods: We used the ...
Gastric cancer at a university teaching hospital in northwestern Tanzania: a retrospective review of 232 cases.

Mabula, J.B.; McHembe, M.D.; Chalya, P.L.; Massaga, F.; Rambau, P.F.; Masalu, N.; Jaka, H.; Koy, M. (BioMed Central, 2012)

BACKGROUND: Despite marked decreases in its incidence, particularly in developed countries, gastric cancer is still the second most common tumor worldwide. There is a paucity of information regarding gastric cancer in ...
Gender aspects on HIV prevention efforts and participation in HIV vaccine trials among Police officers in Dar es Salaam, Tanzania

Tarimo, Edith A. M.; Kakoko, Deodatus C. V; Kohi, Thecla W.; Bakari, Muhammad; Sandstrom, Eric; Siyame, David; Mhalu, Fred; Kulane, Asli (BMC public health, 2018)

Background: For more than three decades, Human Immunodeficiency Virus (HIV) infection and Acquired Immune Deficiency Syndrome (AIDS) continue to dominate the health agenda. In sub-Saharan African countries, women are at ...
Gender Roles and Informal Care for Patients With AIDS A Qualitative Study From an Urban Area in Tanzania

Tarimo, Edith A.M; Kohi, Thecla W; Outwater, Anne; Blystard, Astrid (SAGE, 2009)

As HIV/AIDS imposes an overwhelming pressure on the capacity of an already overburdened health care system in many African countries, families have increasingly been noted to supplement hospital care services for patients ...
Gender-based violence and adherence to anti-retroviral therapy among HIV-infected women attending care and treatment clinic, Mbeya Tanzania.

Robert, L.A. (Muhimbili University of Health and Allied Sciences, 2017)

Background: Approximately 62% of women living with HIV receive antiretroviral therapy (ART) in Tanzania. To maximize the clinical benefits of ART and attain a successful treatment outcome, more than 95 % adherence level ...
Gender-related differences in the prevalence of cardiovascular disease risk factors and their correlates in urban Tanzania

Njelekela, M.A.; Mpembeni, R.; Muhihi, A.; Mligiliche, N.L.; Spiegelman, D.; Hertzmark, E.; Liu, E.; Finkelstein, J.L.; Fawzi, W.W.; Willett, W.C.; Mtabaji, J. (BioMed Central, 2009)

Background: Urban areas in Africa suffer a serious problem with dual burden of infectious diseases and emerging chronic diseases such as cardiovascular diseases (CVD) and diabetes which pose a serious threat to population ...
Gene expression profiles associated with congenital heart disease among children aged 0-59 months at Muhimbili national hospital and Jakaya Kikwete Cardiac Institute, Dar es salaam, Tanzania.

Mariki, H.K. (Muhimbili University of Health and Allied Sciences, 2017)

Background: Congenital heart diseases (CHD) represent the most common birth defect in paediatric population. The majority of cases are caused by a combination of complex genetic alterations and environmental influences. ...
Genetic association of fetal-hemoglobin levels in individuals with sickle cell disease in Tanzania maps to conserved regulatory elements within the MYB core enhancer

Mtatiro, N.S.; Mgaya, J.; Singh, T.; Mariki, H.; Rooks, H.; Soka, D.; Mmbando, B.; Thein, L.S.; Barrett, C.J.; Makani, J.; Cox, E.S.; Menzel, S. (Bio med central, 2015-02)

Background: Common genetic variants residing near upstream regulatory elements for MYB, the gene encoding transcription factor cMYB, promote the persistence of fetal hemoglobin (HbF) into adulthood. While they have ...
Genetic determinants of resistance among ESBL-producing enterobacteriaceae in community and hospital settings in East, Central, and Southern Africa: A systematic review and meta-analysis of prevalence.

Onduru, O.G.; Mkakosya, R.S.; Aboud, S. (Muhimbili University of Health and Allied Sciences, 2021)

ABSTRACT Background: The world prevalence of community and hospital-acquired extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae is increasing tremendously. Bacteria harboring ESBLs are currently the number ...
Genetic relatedness and risk factor analysis of ampicillin-resistant and high-level gentamicinresistant enterococci causing bloodstream infections in Tanzanian children

Aamodt, H.; Mohn, C.S.; Maselle, S.; Manji, P.K.; Willems, R.; Jureen, R.; Langeland, N.; Blomberg, B. (Bio med central, 2015-03)

Background: While enterococci resistant to multiple antimicrobials are spreading in hospitals worldwide, causing urinary tract, wound and bloodstream infections, there is little published data on these infections from ...

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