School of Medicine: Recent submissions

Now showing items 41-60 of 1545

Neonatal resuscitation: EN-BIRTH multi-country validation study. BMC Pregnancy and Childbirth

Ashish, P.C; Peven, K.; Ameen, S., et. al.. (BMC, 2021)

Background: Annually, 14 million newborns require stimulation to initiate breathing at birth and 6 million require bag-mask-ventilation (BMV). Many countries have invested in facility-based neonatal resuscitation equipment ...
Sickle Gen Africa Network. Sickle Cell Disease Genomics of Africa (SickleGenAfrica) Network

Anie, K.A.; Olayemi, E.; Paintsil, V., et. al (BMJ OPEN, 2021)

Objectives: To provide lay information about genetics and sickle cell disease (SCD) and to identify and address ethical issues concerning the Sickle Cell Disease Genomics of Africa Network covering autonomy and research ...
Monoplanar external fixation of comminuted open tibial shaft fractures predicts loss of alignment by one year compared to a statically locked intramedullary SIGN nail

Donnelley, C.A.; von Kaeppler, E.P.; Roberts, H.J. (Muhimbili University of Health and Allied Sciences, 2021)

ABSTRACT Aims: This investigation develops a predictive model for loss of alignment (LOA) following fixation of open tibia fractures. Patients/methods: An analysis was performed of adults with diaphyseal open tibia fractures ...
Evaluation of Root Extract of Cyphostemma Adenocaule (Vitaceae) for Antioxidant Activity, Brine Shrimp Toxicity, and Antiproliferative Activity against Hela Cervical Cancer Cells.

Daniel, Z.; Matata, D.Z.; Machumi, F. (Muhimbili University of Health and Allied Sciences, 2021)

ABSTRACT Cyphostemma adenocaule (Vitaceae) is used by traditional health practitioners in northeastern Tanzania, for treatment of cancer but there is no information available regarding its safety and efficacy. This study ...
Dust exposure and respiratory health among workers in primary coffee processing factories in Tanzania and Ethiopia.

Bråtveit, M.; Wakuma, A.S.; Gloria, S. (Muhimbili University of Health and Allied Sciences, 2021)

ABSTRACT Introduction: In primary coffee factories the coffee beans are cleaned and sorted. Studies from the 80- and 90-ties indicated respiratory health effects among the workers, but these results may not represent the ...
Refugee settlements and cholera risks in Uganda, 2016-2019.

Bwire, G.; Orach, C.G.; Aceng, F.L. (Muhimbili University of Health and Allied Sciences, 2021)

ABSTRACT Introduction: During 2016 to 2019, cholera outbreaks were reported commonly to the Ministry of Health from refugee settlements. To further understand the risks cholera posed to refugees, a review of surveillance ...
The Lancet Global Health Commission on Global Eye Health: vision beyond 2020.

Burton, M.J.; Ramke, J.; Marques, A.P. (Muhimbili University of Health and Allied Sciences, 2021)

ABSTRACT Eye health and vision have widespread and profound implications for many aspects of life, health, sustainable development, and the economy. Yet nowadays, many people, families, and populations continue to suffer ...
Mortality and associated factors among adult patients on tuberculosis treatment in Tanzania: A retrospective cohort study.

Bukundi, E.M.; Mhimbira, F.; Kishimba, R. (Muhimbili University of Health and Allied Sciences, 2021)

ABSTRACT Introduction: Tuberculosis (TB) is the global leading cause of death from an infectious agent. Tanzania is among the 30 high TB burden countries with a mortality rate of 47 per 100,000 population and a case ...
Perspectives on building sustainable newborn screening programs for sickle cell disease: Experience from Tanzania.

Bukini, D.; Nkya, S.; McCurdy, S. (Muhimbili University of Health and Allied Sciences, 2021)

ABSTRACT The prevalence of sickle cell disease is high in Africa, with significant public health effects on the affected countries. Many of the countries with the highest prevalence of the disease also have poor health ...
Influence of gender norms in relation to child's quality of care: follow-up of families of children with SCD identified through NBS in Tanzania.

Bukini, D.; Mbekenga, C.; Nkya, S. (Muhimbili University of Health and Allied Sciences, 2021)

ABSTRACT Introducing newborn screening (NBS) services for sickle cell disease (SCD) in Africa has been proven to be one of the most cost-effective approach to reducing morbidity and mortality associated with this condition. ...
From a Lancet Commission to the NCDI Poverty Network: reaching the poorest billion through integration science.

Bukhman, G.; Mocumbi, A.O; Gupta, N. (Muhimbili University of Health and Allied Sciences, 2021)

ABSTRACT Since its inception in 2016, the Lancet Commission on reframing non-communicable diseases (NCDs) and injuries (NCDIs) for the poorest billion (Lancet NCDI Poverty Commission) has been steadily building a foundation ...
Optimal management of esophageal cancer in Africa: A systemic review of treatment strategies

Buckle, G.C.; Mahapatra, R.; Mwachiro, M. (Muhimbili University of Health and Allied Sciences, 2021)

ABSTRACT Esophageal cancer (EC) is a leading cause of cancer morbidity and mortality in Africa. Despite the high burden of disease, optimal management strategies for EC in resource-constrained settings have yet to be ...
Utilization of pneumococcal vaccine and penicillin prophylaxis in sickle cell disease in three African Countries: assessment among healthcare providers in SickleInAfrica

Brown, B.J.; Madu, A.; Sangeda, R.Z. (Muhimbili University of Health and Allied Sciences, 2021)

ABSTRACT Sickle cell disease is a genetic disease with a predisposition to infections caused by encapsulated organisms, especially Streptococcus pneumoniae. Pneumococcal vaccines and prophylactic penicillin have reduced ...
Formative research to design an implementation strategy for a postpartum hemorrhage initial response treatment bundle (E-MOTIVE): study protocol.

Bohren, M.A.; Lorencatto, F.; Coomarasamy, A. (Muhimbili University of Health and Allied Sciences, 2021)

Background: Postpartum hemorrhage (PPH) is the leading cause of maternal death worldwide. When PPH occurs, early identification of bleeding and prompt management using evidence-based guidelines can avert most PPH-related ...
Maternal HBV viremia and association with adverse infant outcomes in women living with HIV and HBV.

Bhattacharya, D.; Guo, R.; Tseng, C.H. (Muhimbili University of Health and Allied Sciences, 2021)

Background: There is limited information on perinatal outcomes in HIV-hepatitis B virus (HBV) coinfection. Methods: HIV Prevention Trials Network (HPTN) 046 was a randomized double-blind placebo-controlled trial of perinatal ...
Acceptability and perceptions of HIV oral self-testing across settings: A comparative qualitative study among Dominican and Tanzanian female sex workers.

Beckham, S.W.; Karver, T.; Mantsios, A. (Muhimbili University of Health and Allied Sciences, 2021)

Rapid oral HIV self-tests (HIVST) have potential to increase the proportion of people who know their HIV status, especially among stigmatised populations. This study was embedded in two cohorts of female sex workers (FSW) ...
Building sustainable research capacity at higher learning institutions in Tanzania through mentoring of the young research peers

Balandya, E.; Sunguya, B.; Gunda, D.W. (Muhimbili University of Health and Allied Sciences, 2021)

Background: Sustainability of research culture in Sub-Saharan Africa is threatened in part by the lack of a critical mass of young researchers with the requisite skills and interest to undertake research careers. This paper ...
Reducing surgical site infections and mortality among obstetric surgical patients in Tanzania: a pre-evaluation and postevaluation of a multicomponent safe surgery intervention.

Ernest., E.C.; Hellar, A.; Varallo, J. (Muhimbili University of Health and Allied Sciences, 2021)

ABSTRACT Introduction: Despite ongoing maternal health interventions, maternal deaths in Tanzania remain high. One of the main causes of maternal mortality includes postoperative infections. Surgical site infection (SSI) ...
Pentacylic triterpenes from Lavandula coronopifolia: Structure related inhibitory activity on α-glucosidase.

Elsbaey, M.; Mwakalukwa, R.; Shimizu, K. (Muhimbili University of Health and Allied Sciences, 2021)

ABSTRACT Ten pentacyclic triterpenes (1-10) were isolated from Lavandula coronopifolia. We evaluated their α-glucosidase inhibitory activity, and found that the aglycones, 1, 2, 3, 4, 7 and 10 showed superior IC50 values ...
Belief on witchcraft and killing of people with albinism in lack Victoria Zone, Tanzania.

Edmund, J.K. (Muhimbili University of Health and Allied Sciences, 2021)

ABSTRACT Killing of people with albinism and old people has been featuring in Tanzania mass media and worldwide. The main cause of killing old people and people with albinism is witchcraft beliefs. Old women are reported ...

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