Abstract:
Long chain aliphatic methyl ketone series of C7-C15 were tested for repellency activity against the malaria
transmitting mosquito Anopheles gambiae s.s. All methyl ketones produced a dose dependent (P<0.001) repellency
response with 2-tridecanone giving comparable protection efficacy to DEET at 10% and 1% concentrations. Aliphatic
methyl ketones of C7-C10 had lower activity than those of C11-C15. However, within this range compounds with odd carbon
atoms (2-undecanone, 2-tridecanone and 2-pentadecanone) were more effective than compounds with even carbon atoms
(2-decanone and 2- dodecanone). Comparable repellency activity of 2-tridecanone to DEET show that, it may save as
Anopheles gambiae s.s. mosquito repellent.
