Evaluation of ethnomedical claims and brine shrimp toxicity of some plants used in Tanzania as traditional medicines

Kapingu, M.C; Moshi, M. J; Mbwambo, Z. H; Nondo, R. S; Masimba, P. J; Kamuhabwa, A.

dc.contributor.author	Kapingu, M.C
dc.contributor.author	Moshi, M. J
dc.contributor.author	Mbwambo, Z. H
dc.contributor.author	Nondo, R. S
dc.contributor.author	Masimba, P. J
dc.contributor.author	Kamuhabwa, A.
dc.date.accessioned	2014-02-24T04:59:00Z
dc.date.available	2014-02-24T04:59:00Z
dc.date.issued	2006
dc.identifier.citation	Moshi, M. J., Mbwambo, Z. H., Nondo, R. S.,Masimba, P. J., Kamuhabwa, A., Kapingu, M. C., ... & Richard, M. (2006). Evaluation of ethnomedical claims and brine shrimp toxicity of some plants used in Tanzania as Moshi, M. J., Mbwambo, Z. H., Nondo, R. S., Masimba, P. J., Kamuhabwa, A., Kapingu, M. C., ... & Richard, M. (2006). Evaluation of ethnomedical claims and brine shrimp toxicity of some plants used in Tanzania as traditional medicines. African Journal of Traditional, Complementary and Alternative Medicines, 3(3), 48-58	en_GB
dc.identifier.issn	0189-6016
dc.identifier.uri	http://hdl.handle.net/123456789/1410
dc.description	This study evaluated the strength of therapeutic claims on some of plants collected from an ethnomedical survey in 3 districts of Tabora region (Western Tanzania), and also employed the brine shrimp lethality test as a preliminary tool to evaluate other potential biological activities that have not been reported by the traditional healers.	en_GB
dc.description.abstract	Using information from the literature it has been demonstrated that twenty one (21) plants out of 60 (35%) which are used in traditional medicine, in Tabora region (Western Tanzania), are used elsewhere for the treatment of similar conditions or their claims have proven biological results. Ethanol extracts of some of the plants exhibited low, some intermediate, and some high toxicity against brine shrimps. The brine shrimp assay results for Psorospermum febrifugum Spach (Guttiferae) [LC50 12.7µg/ml], agreed with previous reports of established anticancer activity, while for Phyllanthus engleri Pax. (Euphorbiaceae) [LC50 0.47µg/ml]they supported literature reports that it is toxic to rabbits and fish. Despite the therapeutic claims, literature reports, and brine shrimp assay results, more rigorous studies are needed to confirm the therapeutic utility of	en_GB
dc.description.sponsorship	NAPRALERT Data Base at the University of Illinois, Chicago,	en_GB
dc.language.iso	en	en_GB
dc.publisher	African Ethnomedicines Network	en_GB
dc.relation.ispartofseries	African Journal of Traditional, Complementary and Alternative Medicines;Vol. 3, Num. 3,
dc.subject	Ethnomedical claims	en_GB
dc.subject	Toxicity	en_GB
dc.subject	Drug discovery approaches	en_GB
dc.subject	Tanzania	en_GB
dc.title	Evaluation of ethnomedical claims and brine shrimp toxicity of some plants used in Tanzania as traditional medicines	en_GB
dc.type	Article	en_GB