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The burden of hypertension in sub-Saharan Africa: a four-country cross sectional study

Show simple item record Guwatudde, D. Mutyoba, N.J. Kalyesubula, R. Laurence, C. Adebamowo, C. Ajayi, I. Bajunirwe, F. Njelekela, M. Chiwanga, S.F. Reid, T. Volmink, J. Adami, O.H Holmes, D.M. Dalal, S. 2016-09-14T07:03:27Z 2016-09-14T07:03:27Z 2015-12
dc.identifier.citation Guwatudde D, Nankya-Mutyoba J, Kalyesubula R, Laurence C, Adebamowo C, Ajayi I, Bajunirwe F, Njelekela M, Chiwanga FS, Reid T, Volmink J. The burden of hypertension in sub-Saharan Africa: a four-country cross sectional study. BMC public health. 2015 Dec 5;15(1):1. en_GB
dc.identifier.uri (
dc.description.abstract Background: Hypertension, the leading single cause of morbidity and mortality worldwide, is a growing public health problem in sub-Saharan Africa (SSA). Few studies have estimated and compared the burden of hypertension across different SSA populations. We conducted a cross-sectional analysis of blood pressure data collected through a cohort study in four SSA countries, to estimate the prevalence of pre-hypertension, the prevalence of hypertension, and to identify the factors associated with hypertension. Methods: Participants were from five different population groups defined by occupation and degree of urbanization, including rural and peri-urban residents in Uganda, school teachers in South Africa and Tanzania, and nurses in Nigeria. We used a standardized questionnaire to collect data on demographic and behavioral characteristics, injuries, and history of diagnoses of chronic diseases and mental health. We also made physical measurements (weight, height and blood pressure), as well as biochemical measurements; which followed standardized protocols across the country sites. Modified Poison regression modelling was used to estimate prevalence ratios (PR) as measures of association between potential risk factors and hypertension. Results: The overall age-standardized prevalence of hypertension among the 1216 participants was 25.9 %. Prevalence was highest among nurses with an age-standardized prevalence (ASP) of 25.8 %, followed by school teachers (ASP = 23.2 %), peri-urban residents (ASP = 20.5 %) and lowest among rural residents (ASP = 8.7 %). Only 50.0 % of participants with hypertension were aware of their raised blood pressure. The overall age-standardized prevalence of pre-hypertension was 21.0 %. Factors found to be associated with hypertension were: population group, older age, higher body mass index, higher fasting plasma glucose level, lower level of education, and tobacco use. Conclusions: The prevalence of hypertension and pre-hypertension are high, and differ by population group defined by occupation and degree of urbanization. Only half of the populations with hypertension are aware of their hypertension, indicating a high burden of undiagnosed and un-controlled high blood pressure in these populations. en_GB
dc.language.iso en en_GB
dc.relation.ispartofseries Guwatudde et al. BMC Public Health;10.1186/s12889-015-2546-z
dc.subject Prevalence of hypertension en_GB
dc.subject Prevalence of pre-hypertension en_GB
dc.subject Risk factors for hypertension, en_GB
dc.subject Africa en_GB
dc.title The burden of hypertension in sub-Saharan Africa: a four-country cross sectional study en_GB
dc.type Article en_GB

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