Efficacy and safety Of artemether‑lumefantrine for the treatment Of uncomplicated malaria and prevalence Of Pfk13 and Pfmdr1 polymorphisms After a decade of using artemisinin‑based Combination therapy in mainland Tanzania

Ishengoma, D.S.; Mandara, C.I.; Francis, F.; Talundzic, E.; Lucchi, N.W.; Ngasala, B.; Kabanywanyi, A.M.; Mahende, M.K.; Kamugisha, E.; Kavishe, R.A.; Muro, F.; Mohamed, A.; Mandike, R.; Mkude, S.; Chacky, F.; Paxton, L.; Greer, G.; Kitojo, C.A.; Njau, R.; Martin, T.; Venkatesan, M.; Warsame, M.; Halsey, E.S.; Udhayakumar, V.

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dc.contributor.author	Ishengoma, D.S.
dc.contributor.author	Mandara, C.I.
dc.contributor.author	Francis, F.
dc.contributor.author	Talundzic, E.
dc.contributor.author	Lucchi, N.W.
dc.contributor.author	Ngasala, B.
dc.contributor.author	Kabanywanyi, A.M.
dc.contributor.author	Mahende, M.K.
dc.contributor.author	Kamugisha, E.
dc.contributor.author	Kavishe, R.A.
dc.contributor.author	Muro, F.
dc.contributor.author	Mohamed, A.
dc.contributor.author	Mandike, R.
dc.contributor.author	Mkude, S.
dc.contributor.author	Chacky, F.
dc.contributor.author	Paxton, L.
dc.contributor.author	Greer, G.
dc.contributor.author	Kitojo, C.A.
dc.contributor.author	Njau, R.
dc.contributor.author	Martin, T.
dc.contributor.author	Venkatesan, M.
dc.contributor.author	Warsame, M.
dc.contributor.author	Halsey, E.S.
dc.contributor.author	Udhayakumar, V.
dc.date.accessioned	2019-08-22T06:11:08Z
dc.date.available	2019-08-22T06:11:08Z
dc.date.issued	2019
dc.identifier.citation	Ishengoma, D.S., Mandara, C.I., Francis, F., Talundzic, E., Lucchi, N.W., Ngasala, B., Kabanywanyi, A.M., Mahende, M.K., Kamugisha, E., Kavishe, R.A. and Mohamed, A., 2019. Efficacy and safety of artemether-lumefantrine for the treatment of uncomplicated malaria and prevalence of Pfk13 and Pfmdr1 polymorphisms after a decade of using artemisinin-based combination therapy in mainland Tanzania. Malaria journal, 18(1), p.88.	en_US
dc.identifier.uri	http://dspace.muhas.ac.tz:8080/xmlui/handle/123456789/2406
dc.description.abstract	The World Health Organization recommends regular therapeutic efficacy studies (TES) to monitor the performance of first and second-line anti-malarials. In 2016, efficacy and safety of artemether-lumefantrine (AL) for the treatment of uncomplicated falciparum malaria were assessed through a TES conducted between April and October 2016 at four sentinel sites of Kibaha, Mkuzi, Mlimba, and Ujiji in Tanzania. The study also assessed molecular markers of artemisinin and lumefantrine (partner drug) resistance.	en_US
dc.language.iso	en	en_US
dc.publisher	BMC	en_US
dc.relation.ispartofseries	;18(1), p.88.
dc.subject	Efficacy,	en_US
dc.subject	Safety,	en_US
dc.subject	Artemether-lumefantrine,	en_US
dc.subject	Falciparum malaria,	en_US
dc.subject	Tanzania	en_US
dc.title	Efficacy and safety Of artemether‑lumefantrine for the treatment Of uncomplicated malaria and prevalence Of Pfk13 and Pfmdr1 polymorphisms After a decade of using artemisinin‑based Combination therapy in mainland Tanzania	en_US
dc.type	Article	en_US