Abstract:
Background: Children with orofacial tumours and tumour-like lesions who were treated at the Oral and
Maxillofacial Surgery department Muhimbili National Hospital (MNH) were often seen to
have huge swellings which caused marked facial deformity and at times functional difficulties.
The clinical presentation, pathological characteristics and treatment modalities of these lesions
were quite diverse and warranted an investigation to assess their burden in Tanzanian children.
It’s envisaged that the data obtained will help the clinicians at the Oral & Maxillofacial
department MNH and other healthcare institutions in early detection and appropriate
management of children with these lesions.
Objective: To determine the occurrence, clinicopathological characteristics and treatment
modalities of orofacial tumours and tumour-like lesions in children who were treated at
Muhimbili National Hospital, Dar es Salaam, Tanzania during the period from September
2016 to March 2017.
Methods: This cross-sectional hospital-based study was conducted in the Oral and
Maxillofacial Surgery and Otorhinolaryngology departments at MNH. Children aged below 18
years with orofacial tumours and tumour-like lesions or their parents/guardians were
interviewed using a structured questionnaire and clinical examination of the patients were
done and the details recorded in the clinical form. Data analysis was done using statistical
package for social sciences (SPSS) version 20.0. Level of statistical significance was
considered at a P-value of < 0.05.
Results: A total of 121 children aged 4 days old to 17 years (mean= 8.56 years ±5.5 SD)
participated in the study, of whom 52.1% were males. The age groups 0-5 years (38%) and 11-
15 years (28.1%) were most affected by orofacial tumours and tumour-like lesions. Majority
86% of the lesions were benign whereby haemangioma was the most common benign tumour
encountered (16.4%), followed by lymphangioma (13.6%). The most frequent tumour-like
lesion observed was the dentigerous cyst (7.8%), followed by the dermoid cyst and fibroma in 4.1% of participants. Burkitt’s lymphoma and squamous cell carcinoma were the most
common malignant lesions encountered in 23.5% participants in that category. All the lesions
in this study presented with swelling as a common clinical feature in both benign and
malignant tumours and tumour-like lesions. Surgery was the most common modality of
treatment employed.
Conclusion: Orofacial tumours and tumour-like lesions were relatively common in children
seen in this study. Delay and late reporting for treatment was noted in many children with
orofacial tumours and tumour-like lesions. Benign orofacial lesions are more common than
malignant tumours in children in this study. Due to overlapping of clinical presentation
between benign and malignant lesions, clinicians must establish histological diagnosis of
every tumour before initiating definitive treatment. Surgery was the main treatment modality
used for orofacial tumours and tumour-like lesions in this study
