Abstract:
Background: In Tanzania, the uptake of optimal doses (≥3) of sulfadoxine-pyrimethamine for intermittent preven tive treatment of malaria (IPTp-SP) during pregnancy has remained below the recommended target of 80%. Therefore,
this study aimed to investigate the predictors for the uptake of optimal IPTp-SP among pregnant women in Tanzania.
Methods: This study used data from the 2015–16 Tanzania demographic and health survey and malaria indicator
survey (TDHS-MIS). The study had a total of 4111 women aged 15 to 49 who had live births 2 years preceding the
survey. The outcome variable was uptake of three or more doses of IPTp-SP, and the independent variables were age,
marital status, education level, place of residence, wealth index, occupation, geographic zone, parity, the timing of
frst antenatal care (ANC), number of ANC visits and type of the health facility for ANC visits. Predictors for the optimal
uptake of IPTp-SP were assessed using univariate and multivariable logistic regression.
Results: A total of 327 (8%) women had optimal uptake of IPTp-SP doses. Among the assessed predictors, the fol lowing were signifcantly associated with optimal uptake of IPTp-SP doses; education level [primary (AOR: 2.2, 95% CI
1.26–3.67); secondary or higher education (AOR: 2.1, 95% CI 1.08–4.22)], attended ANC at the frst trimester (AOR: 2.4,
95% CI 1.20–4.96), attended≥4 ANC visits (AOR: 1.9, 95% CI 1.34–2.83), attended government health facilities (AOR:
1.5, 95% CI 1.07–1.97) and geographic zone [Central (AOR: 5, 95% CI 2.08–11.95); Southern Highlands (AOR: 2.8, 95% CI
1.15–7.02); Southwest Highlands (AOR: 2.7, 95% CI 1.03–7.29); Lake (AOR: 3.5, 95% CI 1.51–8.14); Eastern (AOR: 1.5, 95%
CI 1.88–11.07)]
Conclusions: The uptake of optimal IPTp-SP doses is still low in Tanzania. The optimal uptake of IPTp-SP was associ ated with attending ANC in the frst trimester, attending more than four ANC visits, attending government health
facility for ANC, having primary, secondary, or higher education level, and geographic zone. Therefore, there is a need
for health education and behavior change interventions with an emphasis on the optimal use of IPTp-SP doses
