Abstract:
Hypoxic Ischemic Encephalopathy (HIE) score may be used to predict neurodevelopment outcome in
infants with birth asphyxia. A total of 140 infants who had a 5 min Apgar score of <7 at birth had
detailed motor and neurodevelopment assessment. Outcome measures were grouped as normal or
abnormal with morbidity (convulsions, abnormal muscle tone and delayed development) or death. The
positive predictive value (PPV) for mortality was 42.3% for moderate HIE and 93.8% for severe HIE.
For severe HIE the PPV was 100%. Thirteen infants had delayed development, the score had PPV of
63.6% for moderate HIE and 100% for severe HIE. The best correlation with outcome was the peak
score of 15 or higher had a PPV of 100%. Specificity was found to be 100% and sensitivity of 14%. The
HIE scoring system is a useful predictor of neurodevelopment outcome at 6 months of age in a resource
poor setting.
