Action leveraging evidence to reduce perinatal mortality and morbidity.

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dc.contributor.author Akuze, J.K.
dc.contributor.author Annersted, S.
dc.contributor.author Benova, L., et. al…
dc.date.accessioned 2023-05-26T06:23:28Z
dc.date.available 2023-05-26T06:23:28Z
dc.date.issued 2021
dc.identifier.citation https://doi.org/10.1186/s12913-021-07155-z en_US
dc.identifier.uri http://dspace.muhas.ac.tz:8080/xmlui/handle/123456789/3381
dc.description.abstract Background: Insufficient reductions in maternal and neonatal deaths and stillbirths in the past decade are adeterrence to achieving the Sustainable Development Goal 3. The majority of deaths occur during the intrapartum and immediate postnatal period. Overcoming the knowledge-do-gap to ensure implementation of known evidence-based interventions during this period has the potential to avert at least 2.5 million deaths in mothers and their offspring annually. This paper describes a study protocol for implementing and evaluating a multi-faceted health care system intervention to strengthen the implementation of evidence-based interventions and responsive care during this crucial period. Methods: This is a cluster randomised stepped-wedge trial with a nested realist process evaluation across 16 hospitals in Benin, Malawi, Tanzania and Uganda. The ALERT intervention will include four main components: i) end-user participation through narratives of women, families and midwifery providers to ensure co-design of the intervention; ii) competency-based training; iii) quality improvement supported by data from a clinical perinatal e-registry and iv) empowerment and leadership mentoring of maternity unit leaders complemented by district based bi-annual coordination and accountability meetings. The trial’s primary outcome is in-facility perinatal (stillbirths and early neonatal) mortality, in which we expect a 25% reduction. A perinatal e-registry will be implemented to monitor the trial. Our nested realist process evaluation will help to understand what works, for whom, and under which conditions. We will apply a gender lens to explore constraints to the provision of evidence-based care by health workers providing maternity services. An economic evaluation will assess the scalability and cost-effectiveness of ALERT intervention. Discussion: There is evidence that each of the ALERT intervention components improves health providers’ practices and has modest to moderate effects. We aim to test if the innovative packaging, including addressing specific health systems constraints in these settings, will have a synergistic effect and produce more considerable perinatal mortality reductions. en_US
dc.publisher Springer Nature en_US
dc.subject perinatal mortality en_US
dc.subject perinatal mortality and morbidity en_US
dc.title Action leveraging evidence to reduce perinatal mortality and morbidity. en_US
dc.title.alternative 1. Action leveraging evidence to reduce perinata: study protocol for a stepped-wedge cluster-randomised trial in Benin, Malawi, Tanzania and Uganda. BMC Health Serv Res. Vol.21(1): 1324. en_US
dc.type Article en_US


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