School of Pharmacy: Recent submissions

Now showing items 41-60 of 172

Factors Associated with Clinical Outcomes of differentiated thyroid cancer following radioiodine Therapy in Tanzania

Mselle, Teddy Frank; Mwaiselage, Julius David; Maunda, Khamza Kibwana; Van Loon, Katherine; Salah, Bouyoucef (Cancer Research Journal, 2019)

Background: Thyroid cancer is the most common endocrine type of malignancy, accounting for 1-5% of all cancers worldwide. Most of the differentiated thyroid cancers are asymptomatic. Surgery is the mainstay of management ...
Clinical emergency care research in low income and middle-income countries opportunities and challenges

Aluisio, A.R.; Aluisio, A.R. (BMJ Glob Health, 2019)

Disease processes that frequently require emergency care constitute approximately 50% of the total disease burden in low-income and middle-income countries (LMICs). Many LMICs continue to deal with emergencies caused by ...
Persistent transmission of Plasmodium Malariae and Plasmodium ovale species in an Area ofdeclining Plasmodium falciparum Transmission in eastern Tanzania

Mikomangwa, W.P.; Minzi, Omary M.S.; Aklillu, Eleni; Kamuhabwa, Appolinary A. R. (BMC, 2019)

Background: Malaria in pregnancy increases the risk of adverse birth outcomes such as low birth weight (LBW), maternal and foetal anemia. In Tanzania, some areas have attained low malaria transmission. However, data on ...
High prevalence and poor linkage to care of transfusion-transmitted infections among blood donors in Dar-es-Salaam, Tanzania

Mohamed, Z.; Kim, in U.; Magesa, Alex; Kasubi, Mabula; Feldman, Sarah F.; Chevaliez, Stephane; Mwakale, Promise; Taylor-Robinson, Simon D.; Thursz, Mark R.; Shimakawa, Yusuke; Rwegasha, John; Lemoine, Maud (John Wiley & Sons Ltd, 2019)

Blood transfusion is one of the most commonly relied upon therapies in sub-Saharan Africa. Existing safeguards recommended include systematic screening for transfusion-transmitted infections and restricted voluntary ...
Immunological perspectives of sub-Saharan populations under prophylaxis against malaria

Bwire, G.M. (Auctores Publishing, 2019)

Immunity is the state of protection against infectious disease conferred either through an immune response generated by immunization or previous infection. Generated immune responses may be long lasting even lifelong or ...
Immunological perspectives of sub-Saharan populations under prophylaxis against malaria

Bwire, G.M.; Mwambete, K.D. (Auctores Publishing, 2019)

Immunity is the state of protection against infectious disease conferred either through an immune response generated by immunization or previous infection. Generated immune responses may be long lasting even lifelong or ...
Performance of Widal test and stool culture in the diagnosis of typhoid fever among suspected patients in Dar es Salaam, Tanzania

Mawazo, A.; Bwire, G.M.; Matee, M.I.N.. (BMC, 2019)

We set an experiment to determine the diagnostic performance of the Widal test and stool culture in typhoid-suspected cases attending tertiary hospitals in Dar es Salaam, Tanzania using blood culture as a golden standard. ...
Factors influencing adherence to antiretroviral therapy among People Living with HIV in an urban and rural setting, Tanzania

Mosha, F.; Sangeda, R.Z.; Ocheng, D.; Risha., P.; Muchunguzi, V.; Vercauteren, J.; Lyamuya, E.; Vandamme, A.; Kaale., E. (East Cent. Afr. J. Pharm., 2019)

Adherence is one of the most crucial determinants of treatment response to antiretroviral therapy (ART). An analytical cross-sectional study was conducted in 24 Care and Treatment Centres (CTC) in Dar es Salaam and Iringa ...
Comparison of malaria treatment Outcome of generic and innovator’s Anti‑malarial drugs containing artemether– Lumefantrine combination in the management Of uncomplicated malaria amongst Tanzanian Children

Kilonzi, M.; Minzi, O.; Mutagonda, R.; Sasi, P.; Kamuhabwa, A.; Aklillu3, E. (BMC, 2019)

Background: In 2006, artemether–lumefantrine (ALU), specifcally Coartem® (Novartis Pharma AG, Basel Switzerland), was approved as the frst-line drug for treatment of uncomplicated malaria in Tanzania. Due to poor availability ...
Level of knowledge among health care Providers on preparation of injectable Artesunate for treatment of severe malaria In public health facilities in Tanzania

Kaaya, C.; Kilonzi, M.; Mlyuka, H.; Marealle, A.I.; Mutagonda, R.; Mikomangwa, W.P. (BMC, 2019)

In Tanzania, seminars and training on the preparation and administration of injectable artesunate were given to health care providers (HCP) during its introduction in 2013. Published evidence on knowledge of its preparation ...
Evaluation of potential inappropriate medication in elderly patients admitted to Muhimbili national hospital using the stopp/start criteria

Makala, B.T. (Muhimbili University of Health and Allied Sciences, 2014)

Background: Prescribing in elderly is a challenging and complex process due to age and physiological related changes which compromise drug handling and response. The process is further complicated by presence of co morbidity ...
Current efficacy of sulphadoxine-pyrimethamine for intermittent preventive treatment of malaria during pregnancy in Dar es salaam

Iddi, A.R. (Muhimbili University of Health and Allied Sciences, 2014)

Background: Intermittent preventive treatment of malaria in pregnancy with Sulphadoxine-Pyrimethamine (IPTp-SP) reduces incidence of malaria, asymptomatic parasitaemia and anaemia, thus improving pregnancy outcome ...
EVALUATION OF PHARMACEUTICAL CARE DELIVERY AND SATISFACTION AMONG CLIENTS ATTENDING COMMUNITY PHARMACIES IN DODOMA MUNICIPALITY-TANZANIA.

Mwamwendesi, G.C. (Muhimbili University of Health and Allied Sciences, 2016)

Background Pharmaceutical care is an ongoing, authorized and systematic quality improvement process. It is designed to review medicine use and/or dispensing patterns and provide feedback of results to dispensers. Recently, ...
Pre & post-operative antibiotic prophylaxis: cesarean section wound complication and factors affecting duration of hospital stay

Mlyuka, H.J. (Muhimbili University of Health and Allied Sciences, 2016)

Background: Antibiotic prophylaxis has been reported to reduce the rate of caesarian section surgical site infection and other complications. Despite such advancement, duration of time spent in hospitals after delivery ...
Assessment of Lipid Profile in HIV Infected Patients Using the First Line Antiretroviral Drugs at Muhimbili National Hospital

OMBENI, W. (Muhimbili University of Health and Allied Sciences, 2014)

Background: The use of antiretroviral therapy has been reported to cause dyslipidemia and increased risk of cardiovascular diseases (CVD) in HIV-infected patients in industrialized countries. The effects of antiretroviral ...
Characterization of Hormonal Receptors and Human Epidermal Growth Factor Receptor-2 in Tissues of Women with Breast Cancer at Muhimbili National Hospital, Dar Es Salaam, Tanzania

Mwakigonja, A.R.; Lushina, N.E; Mwang, A. (Bio Med Central, 2017)

Background: Breast cancer is a leading cause of morbidity and deaths among women worldwide. In Tanzania there is no published data on human epidermal growth receptor-2 (HER2/neu) expression in breast carcinoma. Hormonal ...
Effect of Pharmacogenetics on Plasma Lumefantrine Pharmacokinetics and Malaria Treatment Outcome in Pregnant Women

Mutagonda, R.F.; Kamuhabwa, A.A.R.; Minzi, O.M.S.; Massawe, S.N.; Asghar, M. (BiomedCentral, 2017)

Background: Pregnancy has considerable effects on the pharmacokinetic properties of drugs used to treat uncomplicated Plasmodium falciparum malaria. The role of pharmacogenetic variation on anti-malarial drug disposition ...
Investigation of Factors Affecting Preparedness of Reporting Adverse Drug Reactions among Nurses in Public and Private Hospitals in Dar es Salaam, Tanzania

Mugoyela, V.; Robert, R.; Msota, N. (Scrip.org, 2018)

The current study assessed preparedness among nurses about reporting adverse drug reactions in public and private hospitals. Nurses in hospitals are among health providers very close to patients and are involved in the ...
Assessment of Medicines Cold Chain Storage Conformity with the World Health Organization Requirements in Health Facilities in Tanzania

Muguyela, V.; Ringo, S.; Kaale, E.; Sempombe, J. (2017)

A descriptive study on assessment of medicines cold chain storage conformity with World Health Organization (WHO) requirements in public health facilities was carried out in Dar es Salaam and Dodoma regions. Storage ...
Post Marketing Surveillance of Anti-malarial Medicines in Tanzania

Kaale, E.; Mziray, S.; Mwamwitwa, K.; Kisoma, S.; Augustine, S. (Pharm Regul Aff, 2017)

Background: Presence of substandard and falsified anti-malarial medicines is a major concern in countries with high prevalence of malaria. Systematic assessment and monitoring of anti-malarial medicines circulating on the ...

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