Pharmacy - Theses and Dissertations: Recent submissions

Now showing items 1-20 of 75

Formulation development and evaluation of hydroxyurea dry syrup in sickle cell disease management in pediatrics

Mohamedi, J.A. (Muhimbili University of Health and Allied Sciences, 2020)

Background. Sickle cell disease (SCD) is a genetic disease which affects global population with annual birth of 300,000 SCD infants whom 75% are born in Africa. Tanzania has the highest prevalence (13%) of SCD in the world. ...
Evaluation of Effectiveness and Safety of pharmacological and mechanical labor induction methods among Pregnant Women attending Public Referral Hospitals in Dar es salaam, Tanzania

Erasto, E (Muhimbili University of Health and Allied Sciences, 2021)

Background: Induction of labor aims to initiate or accelerate uterine contraction and cervical ripening for spontaneous vaginal delivery (SVD). Currently, balloon catheter, oxytocin and prostaglandin derivatives are the ...
factors associated with adherence to antihypertensive medications among patients attending hypertensive clinic at JKCI Dares salaam

Magelewanya, A, M (Muhimbili University of Health and Allied Sciences, 2021)

Background: Medication adherence is essential in the treatment of chronic conditions such as hypertension. In Tanzania little is known about adherence status to antihypertensive medications and its associated factors Aim ...
The influence of pharmaceutical regulatory framework in promotion of pharmaceutical industrialization in Tanzania”

Saada, R.H. (Muhimbili University of Health and Allied Sciences, 2021)

Background: Tanzania, has low pharmaceutical manufacturing capacity which causes high imports of pharmaceutical products to meet the local demands. Pharmaceutical regulatory framework is in place to guide local ...
Assessment of the Impact of Covid-19 on the Supply Chain of Essential Health Commodities in Tanzania

Ipagala, P. (Muhimbili University of Health and Allied Sciences, 2021-10)

Background: Essential medicines are those drugs that satisfy the priority healthcare needs of the population. In Tanzania the supply chain of essential health commodities largely depends on imported finished products and ...
Effectiveness of antenatal dexamethasone in reducing respiratory distress syndrome and mortality in preterm neonates: a nested case control study

Kibanga, W. (Muhimbili University of Health and Allied Sciences, 2021-10)

Background: Respiratory distress syndrome (RDS) is a significant cause of preterm neonatal morbidity and mortality globally. Measures like the use of antenatal corticosteroids (ACS) and immediate resuscitation of the ...
Effectiveness of antenatal dexamethasone in reducing respiratory distress syndrome and mortality in preterm neonates: A nested case control study

Kibanga, W, (Muhimbili University of Health and Allied Sciences, 2021)

Background: Respiratory distress syndrome (RDS) is a significant cause of preterm neonatal morbidity and mortality globally. Measures like the use of antenatal corticosteroids (ACS) and immediate resuscitation of the newborn ...
Implementation of the guideline for safe disposal of unfit medicines: a case of regional referral and regional hospitals and regulatory authorities in Dar es salaam.

Kyabula, B,G (Muhimbili University of Health and Allied Sciences, 2020)

ABSTRACT Background: Unfit medicines includes expired, improperly sealed, damaged, unexpired but improperly stored, improperly labelled, counterfeit, substandard and adulterated, prohibited and unauthorized. To prevent ...
Association between levels of high sensitivity c-reactive protein and poor medication adherence among heart failure patients attending care and treatment at Jakaya Kikwete cardiac institute in Dar es salaam, Tanzania

Gabriel, M.M. (Muhimbili University of Health and Allied Sciences, 2018)

ABSTRACT Background: Evidences show that non-adherence to medications in heart failure (HF) patients highly contribute to preventable re-hospitalization, morbidity and mortality. Recently, conjunction of neuro-hormonal ...
Effect of hydration with electrolytes supplementation on cisplatin induced nephrotoxicity among patients with solid tumors at Ocean Road Cancer Institute

Lyimo, T.E. (Muhimbili University of Health and Allied Sciences, 2019)

ABSTRACT BACKGROUND: Nephrotoxicity remains a problem for patients who receive cisplatin based chemotherapy. Electrolyte derangements are known as a complication to chemotherapy with cisplatin and likely to enhance ...
Factors associated with death among TB patients in Tanzania in 2017

Bukundi, E.M. (Muhimbili University of Health and Allied Sciences, 2020)

Abstract Background: Tuberculosis (TB) is the main cause of death from a sole infectious agent worldwide. Tanzania is among the 30 high burden countries with a mortality of 47 per 100,000 population and a case fatality ...
Formulation development of artemether 20 mg/ lumefantrine 120 mg fixed dose combination tablet

Kaswamila, D. (Muhimbili University of Health and Allied Sciences, 2020)

ABSTRACT Background: The World Health Organization (WHO) recommends artemisinin based combination therapies (ACTs) for the treatment of uncomplicated malaria caused by P. falciparum parasite. By combining two active ...
Throat colonization and antibiotic susceptibility of group a β-hemolytic streptococci among rheumatic heart disease patients attending Jakaya Kikwete Cardiac Institute

Wangilisasi, S.P. (Muhimbili University of Health and Allied Sciences, 2018)

Background: Rheumatic Heart Disease (RHD), a complication of Acute Rheumatic Fever (ARF) caused by Group A β-hemolytic Streptococci (GAS) is a major cause of cardiovascular morbidity and mortality in young people in ...
Search for new antibacterial compounds by in vitro biotransformation of selected antibiotics on market using pleurotus ostreatus mushroom

Matinde, R. (Muhimbili University of Health and Allied Sciences, 2020)

ABSTRACT Background:Research and development of the new antibacterial agents are among the strategized measures to combat antimicrobial resistance(AMR). In the recent decades, biotransformation has been demonstrated as ...
Evaluation of potential inappropriate medication in elderly patients admitted to Muhimbili national hospital using the stopp/start criteria

Makala, B.T. (Muhimbili University of Health and Allied Sciences, 2014)

Background: Prescribing in elderly is a challenging and complex process due to age and physiological related changes which compromise drug handling and response. The process is further complicated by presence of co morbidity ...
Current efficacy of sulphadoxine-pyrimethamine for intermittent preventive treatment of malaria during pregnancy in Dar es salaam

Iddi, A.R. (Muhimbili University of Health and Allied Sciences, 2014)

Background: Intermittent preventive treatment of malaria in pregnancy with Sulphadoxine-Pyrimethamine (IPTp-SP) reduces incidence of malaria, asymptomatic parasitaemia and anaemia, thus improving pregnancy outcome ...
EVALUATION OF PHARMACEUTICAL CARE DELIVERY AND SATISFACTION AMONG CLIENTS ATTENDING COMMUNITY PHARMACIES IN DODOMA MUNICIPALITY-TANZANIA.

Mwamwendesi, G.C. (Muhimbili University of Health and Allied Sciences, 2016)

Background Pharmaceutical care is an ongoing, authorized and systematic quality improvement process. It is designed to review medicine use and/or dispensing patterns and provide feedback of results to dispensers. Recently, ...
Pre & post-operative antibiotic prophylaxis: cesarean section wound complication and factors affecting duration of hospital stay

Mlyuka, H.J. (Muhimbili University of Health and Allied Sciences, 2016)

Background: Antibiotic prophylaxis has been reported to reduce the rate of caesarian section surgical site infection and other complications. Despite such advancement, duration of time spent in hospitals after delivery ...
Assessment of Lipid Profile in HIV Infected Patients Using the First Line Antiretroviral Drugs at Muhimbili National Hospital

OMBENI, W. (Muhimbili University of Health and Allied Sciences, 2014)

Background: The use of antiretroviral therapy has been reported to cause dyslipidemia and increased risk of cardiovascular diseases (CVD) in HIV-infected patients in industrialized countries. The effects of antiretroviral ...
Formulation Development and Evaluation of Oro-Dispersible Paediatric Paracetamol Tablets

Maganga, M.B. (Muhimbili University of Health and Allied Sciences, 2016)

Background: Paracetamol is a drug which is administered, both parenterally and orally though mostly orally, for management of pain and fever. Paracetamol liquid dosage forms for paediatrics (syrups and elixirs) dominate ...

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