Medicine - Journals: Recent submissions

Now showing items 81-100 of 720

Mycosis fungoides with spongiosis: a case report.

Kashabano, J.J.; Rugengamazi, E.; Matiku, S.B. (2023)

ABSTRACT Background: Mycosis fungoides (MF) is the most common form of cutaneous T-cell lymphoma (CTCL). CTCL are an uncommon, heterogeneous group of non-Hodgkin lymphomas (NHLs) of T- and B-cell origin where the skin is ...
Patient reported experience measures on HIV viral load testing at public health facilities in Dar es Salaam, Tanzania: A convergent mixed method study.

Kalori, P.M.; Shayo, G.A.; Shayo, E.H. (2023)

ABSTRACT While viral load (VL) testing is critical to effective treatment of human immunodeficiency virus (HIV), little is known about patients’ experiences with, and barriers to VL-testing in the context of HIV infection. ...
Development of the sickle Pan-African research consortium registry in Tanzania: Opportunity to harness data science for sickle cell disease. Frontiers in Hematology.

Kandonga, D.; Sangeda, R.Z.; Masamu, U. (2023)

ABSTRACT Background: Sickle cell disease (SCD) is a severe hereditary form of anemia that contributes between 50% and 80% of under-five mortality in Africa. Eleven thousand babies are born with SCD annually in Tanzania, ...
Evaluation of the Performance of Copper Sulphate and Hemocue Methods for Haemoglobin Estimation among Blood Donors in Dar Es Salaam, Tanzania.

Kamori, D.; Mwanga, G.; Chamba, C. (2023)

ABSTRACT Background: The National Blood Transfusion Service (NBTS) in Tanzania uses the Copper Sulphate (CuSO4) gravimetric method to estimate hemoglobin (Hb) in blood donors. However, this and other point-of-care methods, ...
Emerging integrase strand transfer inhibitor drug resistance mutations among children and adults on ART in Tanzania: findings from a national representative HIV drug resistance survey.

Kamori, D.; Barabona, G.; Rugemalila, J. (Muhimbili University of Health and Allied Sciences, 2023)

ABSTRACT Background: Despite the scale-up of ART and the rollout in Tanzania of dolutegravir, an integrase strand transfer inhibitor (INSTI), treatment success has not been fully realized. HIV drug resistance (HIVDR), ...
Dolutegravir resistance in Sub-Saharan Africa: Should resource-limited settings be concerned for future treatment?

Kamori, D.; Barabona, G. (Muhimbili University of Health and Allied Sciences, 2023)

ABSTRACT In Sub-Saharan Africa (SSA) the burden of non-nucleoside reverse transcriptase inhibitors (NNRTI) HIV drug resistance (HIVDR) has been high over the years. Therefore, in 2018 the World Health Organization (WHO) ...
Postoperative Complications and Factors Associated with Surgical Site Infection at Muhimbili National Hospital, Dar es Salaam, Tanzania: A cross-Sectional study

Mbowella, A.; Mchembe, M.; Massawe, G. (Muhimbili University of Health and Allied Sciences, 2024)

ABSTRACT Background: Postoperative complications are a leading cause of morbidity and mortality to surgical patients. Different complications are encountered in clinical practice, however surgical site infection (SSI) ...
Prevalence, treatment, and factors associated with Cryptococci meningitis post introduction of integrase inhibitors antiretroviral based regimens among People Living with HIV in Tanzania.

Minja, M.; Mbilinyi, T.; Mkinga, B. (Muhimbili University of health and Allied Sciences, 2024)

ABSTRACT Objective: This study aimed to assess the prevalence of Cryptococcal Meningitis (CM), treatment practice, and the associated factors post-introduction of Tenofovir Lamivudine and Dolutegravir (TLD) regimen among ...
Direct Comparison of Standard and Ultrasensitive PCR for the Detection of Plasmodium falciparum from Dried Blood Spots in Bagamoyo, Tanzaniia

Markwalter, C; Ngasala, B; Mowatt, T; Basham, C; Park, Z; Loya, M (The American Journal of Tropical Medicine and Hygiene, 2021)

t. Ultrasensitive PCR used in low-transmission malaria-endemic settings has revealed a much higher burden of asymptomatic infections than that detected by rapid diagnostic tests (RDTs) or standard PCR, but there is ...
Development of a Mobile Health Application for HIV Prevention Among At-Risk Populations in Urban Settings in East Africa: A Participatory Design Approach

Mauka, W; Mbotwa, C; Moen, K (. JMIR Formative Research, 2021)

Background: There is limited evidence in Africa on the design and development of mobile health (mHealth) applications to guide best practices and ensure effectiveness. A pragmatic trial for HIV pre-exposure prophylaxis ...
. Immunological and Virological Outcomes among Treatment Experienced HIV-Infected Patients on Dolutegravir Regimen in Tanzania. Tanzania Medical Journal. Vol.32 (4):28-39

Maganda, B.; Kavuraya., B.; Mutagonda, R. (2021)

Introduction: The integrase inhibitor dolutegravir (DTG) has recently replaced the non nucleoside reverse transcriptase inhibitors (efavirenz and nevirapine) in several Sub-Saharan African countries, including Tanzania. ...
Determinants of treatment-seeking behavior during self-reported febrile illness episodes using the socio-ecological model in Kilombero District, Tanzania

Mburu, C; . Bukachi, S; Shilabukha, K; Tokpa, K; Ezekiel, M; Fokou, G (BMC Public Health, 2021)

Background: Febrile diseases in Sub-Saharan Africa cause acute and chronic illness. Co-infections are common and these diseases have a complex etiology that includes zoonoses. For the implementation of appropriate ...
Predictors of fear of childbirth and depressive symptoms among pregnant women: a cross-sectional survey in Pwani region, Tanzania

Massae, A; Larsson, M; Leshabari, S; Mbekenga, C; Pembe, A; Svanberg, A (BMC Pregnancy and Childbirth, 2021)

Background: Many women experience fear of childbirth (FoB) and depressive symptoms (DS) during pregnancy, but little is known about FoB among Tanzanian women. The current study aimed to assess the prevalence of FoB and ...
Predominance of PVL-negative community-associated methicillin-resistant Staphylococcus aureus sequence type 8 in newly diagnosed HIV-infected adults, Tanzani

Manyahi, J; Moyo, S; Aboud, S; Langeland, N; Blomberg, B (Europe Journals of microbiology and infection diseases, 2021-02-14)

Abstract Difficult-to-treat infections caused by methicillin-resistant Staphylococcus aureus (MRSA) are of concern in people living with HIV infection as they are more vulnerable to infection. We aimed to identify molecular ...
riginal reports Survival in Cervical Cancer and Its Predictors at Ocean Road Cancer Institute From January to December 2012

Khami, S; Mrema, A; Katanga, J; . Lugina, E (JCO Global Oncology, 2021-01)

Cervical cancer is a major public health problem. With an estimated 570,000 new cases and 314,000 deaths in 2018 worldwide, this disease ranks as the fourth most frequently diagnosed cancer and the fourth cause of ...
No evidence of SARS-CoV-2 transmission through transfusion of human blood products: A systematic review

Mawalla, W; Njiro, B; Bwire, G; Nasser, A; Sunguya, B (. EJHaem, 2021-07-06)

The presence of viral nucleic material in the circulation poses a theoretical risk of transmission through transfusion. However, little is known about the possibility of the actual transmission through transfusion or ...
WHO/INRUD core prescribing indicators and antibiotic utilization patterns among primary health care facilities in Ilala district, Tanzania

iKilipamwambu, A; Bwire, G; Myemba, D; Njiro, B; Majigo, M (JAC-Antimicrobial Resistance,, 2021-03-21)

Results: A total of 604 prescriptions were reviewed. Patients had median age (IQR) of 15 (4–31) years with majority having upper respiratory tract infection 33.3% (n " 201), urinary tract infection 31.1% (n " 188) or diar ...
Control of hemolysis in patients with PNH

Luzzatto, L. (The Journal of the American Society of Hematology, 2021-11)

Paroxysmal nocturnal hemoglobinuria (PNH) is characterized by the triad of intravascular hemolysis (IVH), a tendency to thrombosis, and an element of bone marrow failure. With the introduction of the anti-C5 antibody ...
White Paper on Early Critical Care Services in Low Resource Settings

LOSONCZY, L.; GIRMA, B.; ROUHANI, S.; PAPALI, A.; et al (Annals of global health, 2021)

This White Paper has been formally accepted for support by the International Federation for Emergency Medicine (IFEM) and by the World Federation of Intensive and Critical Care (WFICC), put forth by a multi-specialty ...
Facility and patient barriers in the implementation of isoniazid preventive therapy for people living with HIV attending Care and Treatment Centers, Songea Municipality, Tanzania

Komba, F; Frumence, G (Pan African Medical Journal,, 2021-01-22)

Introduction: isoniazid preventive therapy for people living with HIV is an essential public health intervention in low-income countries with high tuberculosis and HIV burden. Despite available evidence that it is ...

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