Pharmacy - Journals: Recent submissions

Now showing items 61-80 of 90

Comparison of bioavailability between the most available generic tablet formulation containing artemether and lumefantrine on the Tanzanian market and the innovator’s product

Minzi, O. M.; Marealle, I. A.; Shekalaghe, S.; Juma, O.; Ngaimisi, E.; Chemba, M.; Rutaihwa, M.; Abdulla, S.; Sasi, P. (BioMed Central, 2013)

Background: Existence of anti-malarial generic drugs with low bioavailability marketed on sub-Saharan Africa raises a concern on patients achieving therapeutic concentrations after intake of such products. This work ...
Microbial contamination of nonsterile pharmaceuticals in public hospital settings

Mugoyela, V.; Mwambete, K. (Dovepress, 2010-09-09)

Purpose: Contamination of pharmaceuticals with microorganisms irrespective whether they are harmful or nonpathogenic can bring about changes in physicochemical characteristics of the medicines. Although sterility is not ...
Application of basic pharmacology and dispensing practice of antibiotics in accredited drug-dispensing outlets in Tanzania

Minzi, O. M.; Manyilizu, V. S. (Dove Medical Press Ltd, 2013)

Background: Provision of pharmaceutical services in accredited drug-dispensing outlets (ADDOs) in Tanzania has not been reported. This study compared the antibiotics dispensing practice between ADDOs and part II shops, or ...
A fast and reliable reversed phase high performance liquid chromatography method for simultaneous determination of selected anti-retroviral and lumefantrine in human plasma

Maganda, Betty; Heudi, Olivier; Cortinovis, Agness; Picard, Franck; Kretz, Olivier; Minzi, Omary (Science Direct, 2013-03-01)

A fast and reliable high performance liquid chromatography (HPLC) method with UV diode array detection for simultaneous quantitative analysis of the anti-retroviral drugs, nevirapine (NVP) and efavirenz (EFV) and the ...
Challenges of secondary immunodeficiency and drug resistant opportunistic pathogens in developing countries.

Mwambete, K. D.; Justin-Temu, M. (FORMATEX, 2013)

The immune system is composed of a variety of cells and proteins viz. lymphocytes, phagocytes, and cytokines, for which one of the principal functions is microbial defense. Abnormalities of the immune system (IS), ...
Reforms: a quest for efficiency or an opportunity for vested interests'? a case study of pharmaceutical policy reforms in Tanzania

Mori, A. T.; Kaale, E. A.,; Risha, P (BioMed Central, 2013)

Background: Regulation of the pharmaceutical sector is a challenging task for most governments in the developing countries. In Tanzania, this task falls under the Food and Drugs Authority and the Pharmacy Council. In 2010, ...
The role of evidence in the decision-making process of selecting essential medicines in developing countries: the case of Tanzania

Mori, A. T.; Kaale, E. A.; Ngalesoni, F.; Norheim, O. F.; Robberstad, B (PloS one, 2014-01-08)

Background: Insufficient access to essential medicines is a major health challenge in developing countries. Despite the importance of Standard Treatment Guidelines and National Essential Medicine Lists in facilitating ...
In vitro antimicrobial activity of Albizia amaraleaves from Lindi region, Tanzania.

Baltazary, G.; Nshimo, C. M. (Muhimbili University of Health and Allied Health Sciences, 2010)

Ethnopharmacological relevance: Aqueous Albizia amara leaf extract is used by traditional healers for treatment of diarrheal diseases. Aim of study: To evaluate the antimicrobial activity of chromatographic fractions ...
Reforms: a quest for efficiency or an opportunity for vested interests'? a case study of pharmaceutical policy reforms in Tanzania.

Mori, Amani T.; Kaale, Eliangiringa A.; Risha, Peter (BioMed Central, 2013)

Background Regulation of the pharmaceutical sector is a challenging task for most governments in the developing countries. In Tanzania, this task falls under the Food and Drugs Authority and the Pharmacy Council. In ...
Importance of ethnicity, CYP2B6 and ABCB1 genotype for efavirenz pharmacokinetics and treatment outcomes: a parallel-group prospective cohort study in two sub-Saharan Africa populations

Ngaimisi, E.,; Habtewold, A.; Minzi, O.; Makonnen, E.; Mugusi, S.; Amogne, W.; Yimer, G; Riedel, K; Janabi, M; Aderaye, G; Mugusi, F; Bertilsso, L; Aklillu, E; Burhenne, J (PloS one, 2013-07-05)

Objectives: We evaluated the importance of ethnicity and pharmacogenetic variations in determining efavirenz pharmacokinetics, auto-induction and immunological outcomes in two African populations. Methods: ART naı¨ve HIV ...
Knowledge of sexually transmitted diseases among secondary school students in Dar es Salaam, Tanzania

Mwambete, K.D; Mtaturu, Z. (Elsevier, 2006)

Background: In Tanzania, it is considered a taboo for teachers and parents to talk with children about sexual matters including sexually transmitted diseases (STDs) in schools and at home because of cultural and religious ...
Microbiological Assessment of Commercially Available Quinine Syrup and Water for Injections in Dar Es Salaam, Tanzania

Mwambete, K.D; Justin-Temu, M.; Fazleabbas, F.S (Pharmacotherapy Group, 2009)

Purpose: To conduct microbiological assessment of commercially available quinine syrups and water for injection in Dar es Salaam, Tanzania. Methods: This was a cross-sectional study conducted in Dar es Salaam Region. ...
Chemical Composition and in vitro Antimicrobial Activity of the Essential oils of two Helichrysum Species from Tanzania

Bougatsos, C; Ngassapa, O; Runyoro, D.K.B; Chinou, I.B (Verlag der Zeitschrift für Naturforschung, Tübingen, 2004)

The chemical composition of the essential oils obtained from the aerial parts of Helichrysum cymosum and H. fulgidum, from Tanzania, were analyzed by GC and GC/MS. A total of sixty-five compounds, representing 92.4% and ...
Health professions educators as agents of change in Tanzania: Creativity to implement new curricula

Mloka, Doreen; Omer, Selma; Mkony, Charles; Kisenge, Rodrick; Macfarlane, Sarah; O’Sullivan, Patricia (Macmillan Publishers Ltd., 2012)

Muhimbili University of Health and Allied Sciences (MUHAS) strives to instill in its graduates skills and competencies appropriate to serving the Tanzanian population well. MUHAS leadership, working in collaboration ...
Next-generation insights into regulatory T cells: expression profiling and FoxP3 occupancy in Human.

Birzele, F.; Fauti, T.; Stahl, H.; Lenter, M.C.; Simon, E.; Knebel, D.; Weith, A.; Hildebrandt, T.; Mennerich, D. (2011)

Regulatory T-cells (Treg) play an essential role in the negative regulation of immune answers by developing an attenuated cytokine response that allows suppressing proliferation and effector function of T-cells (CD4(+) ...
Screening of Tanzanian medicinal plants for anti-Candida activity.

Runyoro, DK; Matee, M.I.; Ngassapa, O .D.; Joseph, C.C.; Mbwambo, Z.H. (BioMed Central, 2006)

BACKGROUND: Candida albicans has become resistant to the already limited, toxic and expensive anti-Candida agents available in the market. These factors necessitate the search for new anti-fungal agents. METHODS: ...
Application of basic pharmacology and dispensing practice of antibiotics in accredited drug-dispensing outlets in Tanzania.

Minzi, O.; Manyilizu, V. (Dove Medical Press, 2013)

BACKGROUND: Provision of pharmaceutical services in accredited drug-dispensing outlets (ADDOs) in Tanzania has not been reported. This study compared the antibiotics dispensing practice between ADDOs and part II shops, ...
Priority setting for the implementation of artemisinin-based combination therapy policy in Tanzania: evaluation against the accountability for reasonableness framework.

Mori, A.T.; Kaale, E.A. (BioMed Central, 2012)

BACKGROUND: Priority setting for artemisinin-based antimalarial drugs has become an integral part of malaria treatment policy change in malaria-endemic countries. Although these drugs are more efficacious, they are also ...
Unit of Pharmacology and Therapeutics, Muhimbili University of Health and Allied Sciences, Dar Es Salaam, Tanzania.

Minzi, O.; Gustafsson, L.; Mugoyela, V. (2011)

BACKGROUND: Adherence to antiretroviral treatment (ART) is important to achieve treatment success in human immunodeficiency virus (HIV)-infected patients. Most HIV clinics apply the patient self-report (PSR) method. ...
Self-initiation of antiretroviral therapy in the developing world: the involvement of private pharmacies in an HIV program.

Minzi, O.M.; Kagashe, G.A.; Buma, D. (Dove Medical Press, 2012)

BACKGROUND: Self-initiation to antiretroviral treatment (ART) exposes the patient to the risk of drug toxicity, poor adherence to treatment, and escalates the development of drug resistance. OBJECTIVES: To determine the ...

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