Screening of Tanzanian medicinal plants for anti-Candida activity.

Runyoro, DK; Matee, M.I.; Ngassapa, O .D.; Joseph, C.C.; Mbwambo, Z.H.

dc.contributor.author	Runyoro, DK
dc.contributor.author	Matee, M.I.
dc.contributor.author	Ngassapa, O .D.
dc.contributor.author	Joseph, C.C.
dc.contributor.author	Mbwambo, Z.H.
dc.date.accessioned	2013-03-28T10:41:43Z
dc.date.available	2013-03-28T10:41:43Z
dc.date.issued	2006
dc.identifier.citation	Runyoro, D. K., Matee, M. I., Ngassapa, O. D., Joseph, C. C., & Mbwambo, Z. H. (2006). Screening of Tanzanian medicinal plants for anti-Candida activity. BMC complementary and alternative medicine, 6(1), 11.
dc.identifier.other	PMID: 16571139
dc.identifier.uri	http://hdl.handle.net/123456789/745
dc.description.abstract	BACKGROUND: Candida albicans has become resistant to the already limited, toxic and expensive anti-Candida agents available in the market. These factors necessitate the search for new anti-fungal agents. METHODS: Sixty-three plant extracts, from 56 Tanzanian plant species obtained through the literature and interviews with traditional healers, were evaluated for anti-Candida activity. Aqueous methanolic extracts were screened for anti-Candida activity by bioautography agar overlay method, using a standard strain of Candida albicans (ATCC 90028). RESULTS: Twenty- seven (48%) out of the 56 plants were found to be active. Extracts of the root barks of Albizia anthelmintica and Balanites aegyptiaca, and roots of Plectranthus barbatus showed strong activity. CONCLUSION: The extracts that showed strong anti-Candida activity are worth of further investigation in order to isolate and identify the active compounds.	en_GB
dc.language.iso	en	en_GB
dc.publisher	BioMed Central
dc.relation.ispartofseries	BMC Complement Altern Med. 6:11.
dc.subject	Tanzanian medicinal plants	en_GB
dc.subject	Anti-Candida activity	en_GB
dc.title	Screening of Tanzanian medicinal plants for anti-Candida activity.	en_GB
dc.type	Article	en_GB