A New Isoflavone Glycoside from Dalbergia vacciniifolia (Fabaceae).

Abstract

Institute of Traditional Medicine, Muhimbili University of Health and Allied Sciences, P.O. Box 65001, Dar es Salaam, Tanzania.

5,5'-Dihydroxy-2',4'-dimethoxy-7-[(6-O-β-d-apiofuranosyl-β-d-glucopyranosyl)-oxy] isoflavone (1) was isolated as the major constituent of Dalbergia vacciniifolia root bark ethanol extract together with the four known compounds 5,7-dihydroxy-2',4',5'-trimethoxyisoflavone (3), 5,7-dihydroxy-2',4'-dimethoxy-isoflavone (4), 5-hydroxy-2',4',7-trimethoxyisoflavone (5) and 7-hydroxy-2',4',5'-trimethoxyisoflavone (6). Identification of compounds was achieved through extensive analysis of 1D and 2D NMR and MS spectroscopy.